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The Mayo Hotel
115 West 5th Street
Tulsa, OK 74103
+1 918 582 6296

The Mayo Hotel

West 5th Street,
Tulsa, OK,
United States


Perfectly situated in the heart of Downtown Tulsa, the Financial District and the Deco District, The Mayo stands out from other Tulsa hotels with a convenient location just steps away from:

  • Federal Court House
  • Cox Business Center
  • BOK Center
  • Tulsa Performing Arts Center
  • Brady Arts District
  • Brady Theater
  • Blue Dome Entertainment District
  • Guthrie Greens
  • Philbrook Museum Downtown
  • Cain’s Ballroom
  • ONEOK Field
  • OSU Medical
  • Many local businesses

And just a few miles from:

  • Tulsa International Airport
  • OSU-Tulsa
  • Utica Square
  • Brookside
  • Gilcrease Museum
  • St. John Hospital
  • Hillcrest Hospital
  • University of Tulsa


Directions to The Mayo Hotel



From the Tulsa International Airport:

  • Exit the airport and follow Highway 11 West.
  • Take the First Street exit on the left.
  • Proceed to Cheyenne Ave.
  • Turn Left on Cheyenne Ave.
  • Proceed to 5th Street.
  • Hotel is on the left.

From NW Arkansas and East:

  • Take Highway 412 W.
  • Bear right at I-244 W/US-412 W.
  • Exit 6B on left to merge onto I-44 W/US-75 S.
  • Exit onto E 7th St.
  • Turn Right on S Boulder Ave.
  • Turn left on W. 5th Street.
  • Hotel is on the right.

From Joplin, Missouri and Northeast:

  • Take I-44 W/US-412 W.
  • Bear right at I-244 W/US-412 W.
  • Take exit 6B on the left to merge onto I-44 W/US-75 S.
  • Exit onto E 7th St. Turn Right on S Boulder Ave.
  • Turn Left on W. 5th Street.
  • Hotel is on the right.

From Muskogee and Southeast:

  • Take the Muskogee Turnpike until it merges with Highway 51 West.
  • Continue on OK 51/64.
  • Exit on Cheyenne Ave/Denver Ave.
  • Bear Right on the exit ramp.
  • Turn Left onto Boulder Ave.
  • Turn Left on W. 5th Street.
  • Hotel is on the right.

From Oklahoma City and West:

  • Take the Turner Turnpike toward Tulsa.
  • Follow I-44 E.
  • Bear left at 1-244E.
  • Take exit 4c to merge onto W 7th Street.
  • Turn Left onto Boulder Ave.
  • Turn Left on W. 5th Street.
  • Hotel is on the right.

From Bartlesville and North:

  • Take US 75 South.
  • Exit onto E 7th Street.
  • Turn Left onto Boulder Ave.
  • Turn Left on W. 5th Street.
  • Hotel is on the right.

From Stillwater and West:

  • Take US-412 East.
  • Take the OK-51/US-64/I-244/US-75 exit right.
  • Exit 4b to merge left onto I-244W/OK-51E/US-64E.
  • Take the 13th Street Exit.
  • Turn left at W 13th St.
  • Turn left at S Denver Ave.
  • Turn right at W 6th St.
  • Turn left at S. Boulder Ave.
  • Turn Left on W. 5th Street.
  • Hotel is on the right.